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Carney Conversations: What can drunk flies tell us about addiction?

Join the Carney Institute for Brain Science for a conversation about the roots of addiction with Karla Kaun, Robert and Nancy Carney Assistant Professor of Neuroscience at Brown University. Held on May 18, 2020, this event was moderated by Diane Lipscombe, Reliance Dhirubhai Ambani Director of the Carney Institute, and Christopher Moore, associate director of the Carney Institute.

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Life and Science in the Lab

A compact genome, tiny brain, and impressive toolbox of sophisticated neurogenetic tools make the fly an excellent model to understand the neural substrate of behavior. We use the powerful molecular and genetic tools available in the fly to investigate the neural substrates of drug reward at the molecular and cellular level.

Learn about collaborative brain science at Brown University

Drosophila show remarkably long-lasting memories for a cue associated with an intoxicating dose of alcohol. We investigate the neural circuitry and associated molecular mechanisms within the fly brain that regulate this memory.

Our approach combines behavioural neuroscience, neuropharmacology, functional imaging, genetics, cell biology, molecular biology, biochemistry, bioinformatics and computer science in order to understand the mechanisms regulating memories for a drug experience.